ConA

CAS No.: 11028-71-0

Grade: BR

Hemagglutination activity: ≤ 64 µ g / ml

Physicochemical properties: salt free lyophilized powder purified by affinity chromatography. It is dissolved in water, physiological saline or buffer, and the solution is clear without insoluble substances. A plant lectin extracted from the seeds of concanavalin and pea. It is a tetrameric globulin with a molecular weight of 102000. Each subunit contains 237 amino acid residues, with a molecular weight of 25500, binds one Ca2 + and one Mn2 +, and contains a sugar binding site. Be able to α- Mannose α- Glucose (on cell membrane glycoprotein) binds specifically, and the binding site requirements are α- D-mannopyranose or α- The C-3 / C-4 and C-6 in the six membered ring of D glucopyranose are unsubstituted hydroxyl groups. Be able to communicate with α- The 1,2 glycosidic linked mannobiose and mannotriose have the highest affinity

Purpose: biochemical research. It is mitogen, which can stimulate T lymphocytes, agglutinate red blood cells and animal sperm, inhibit the movement of tumor cells, and prolong the survival time of xenotransplantation. It is an important biochemical and immune research reagent.

Storage: 2 ~ 8 ℃