lentinan

CAS No.: 37339-90-5

Molecular formula: (c42h70o35) n

Grade: BR

Purity: >50%

Physicochemical properties: yellowish brown powder lentinan is extracted from Lentinus edodes, with β- D (1 → 3) glucan residue as the main chain, with β- (1 → 6) dextran with side chain dextran residues. Lentinan is a gray white powder, mostly acidic polysaccharide, soluble in water and dilute alkali, especially soluble in hot water, insoluble in ethanol, acetone, ethyl acetate, ether and other organic solvents, and its aqueous solution is transparent and viscous.

Purpose: in biochemical research, lentinan is a special immune adjuvant guided by thymus dependent T cells and participated by macrophages. It can recognize antigen macrophages in the spleen and liver, promote the production of lymphocyte activating factors, release various auxiliary T cell factors, and enhance the phagocytosis rate of host peritoneal macrophages. When lentinan is injected into the host for several hours, some serum factors with physiological activities, such as acute phase protein inducer, vasodilation and hemorrhage inducer, IL-1 production inducer The levels of IL3 and colony stimulating factor reached the peak. After these factors act on lymphocytes, hepatocytes and vascular endothelial cells, they produce many effective immune responses, and lead to the maturation, differentiation, proliferation and peripheral release of precursor T cells in the thymus.

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