ICDH/Isocitrate dehydrogenase CAS:9028-48-2
Item No.: E0161
Store at: 2~8°C
product name:ICDH;Isocitrate dehydrogenase;Isocitric Dehydrogenase (NADP) from porcine heart;Threo-Ds-Isocitrate: NADP+ oxidoreductase
Grade:BR
Vitality:3~20 units/mg protein (approx. 0.1% of that activity is obtained with NAD as cofactor.)
Vitality definition:One unit will convert 1.0 μmole of isocitrate to α-ketoglutarate per min at pH 7.4 at 37 °C
Physicochemical properties: suspension, buffered aqueous glucose solution. Molecular weight about 61000
Purpose: biochemical research. NAD + - dependent isocitrate dehydrogenase is a nuclear coding mitochondrial enzyme that participates in the tricarboxylic acid cycle and is responsible for catalyzing the oxidative decarboxylation of isocitrate α- Ketoglutarate is the rate limiting enzyme in the circulation path. It plays a role in enzymatic properties, subunit composition, gene cloning, protein assembly and transport.